Value of core needle biopsy in histopathological and immunohistochemical assessment of liver tumors

Introduction: Liver is the most commonly involved organ by metastatic disease. Secondary tumors are more frequent lesion forming than 75%, while primary cancers of liver formed less 25%. Imaging according to LI-RAD can give a clue for nature live particularly hepatocellular carcinoma. biopsy still golden standard surveillance histopathological diagnosis tumor; however, it traumatic procedure, but its value in reaching definite superior imaging technique. Tru cut open and considered nowadays as preferable technical way sampling tissue that be applied both histopathology immunohistochemistry. lesions were encountered originated from lung, breast, Pancreatobiliary tract GIT, female genital tract, prostate others. Objectives Study: To assess efficacy examination immunohistochemical study identification type origin tumors. Methodology: This cross sectional conducted Al-Sadr Teaching Hospital Al-Najaf City, Iraq January 2019 till December 2021.